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. 2021 Jun 6;21:190. doi: 10.1186/s12890-021-01553-z

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — IL4 and IL6 affected the JAK2-STAT pathway in EML4-ALK-positive cells. a STAT3 and STAT6 were phosphorylated and translocated to the nuclei of H2228 cells following IL4 or IL6 treatment. b Microarray analysis of H2228 cells stimulated or not with IL4. The heat map identifies modified proteins associated with the JAK2-STAT pathway, the regulation of the actin cytoskeleton, the cell cycle, cell adhesion, and the positive regulation of cell proliferation