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. 2021 Jun 5;20:112. doi: 10.1186/s12934-021-01601-7

Table 1.

Prebiotic role of various algae strains on growth promotion of probiotics and related health improvements

Microalgae sp. Probiotic Microalgae conc
(mg. ml−1)
Main focus
Of study
Other remarks Reference
Chlorella vulgaris Lactobacillus brevis 0.1–1.5% Improving the probiotic growth, health, product yield and other desirable properties Algae shortening the log phase, improving lactic acid yield, enzyme activity and acidifying activity of probiotics [20]
Euglena gracilis Streptococcus iniae ND Development as animal feed, paramylon activity was tested Immunostimulant activity offered to the animal host [21]
Pavlova pinguis Phaeobacter inhibens ND Disease management in bivalve Vcoralliilyticus Vibrio sp. infection reduction for reducing the mortality of larval shellfish [22]
Chlorella vulgaris and Spirulina platensis Lactic acid bacteria 3 Supplementing microalgae in milk products for improving its storage and self-life Increasing the viability of probiotics in final product but also the sensory attributes [23]
Euglena gracilis

Bacillus licheniformis

or B. subtilis

ND Development as animal feed, β-glucan was tested in poultry, cow, horses, dogs, cats, birds and reptiles Improved the health and immune system of animal hosts [24]
Spirulina platensis Lactococcus lactis sp. 1 Supplementing microalgae in yogurt to improve health benefits due to probiotic enrichment Increasing the viability of probiotics and lactic acid bacteria [25]
Spirulina platensis Lactococcus lactis sp. 1 Supplementing microalgae in yogurt to improve health benefits due to healthy bacterial enrichment Increasing the viability of probiotics and lactic acid bacteria [26]
Phaeodactylum triconutum, Tetraselmis chuii Bacillus subtilis ND Developed as animal feed, effect of protein fraction was examined Immune system was improved and intestinal adsorption was increased [27]
Spirulina platensis Bifidobacterium bifidum and other 1–2 Feed for animals suffering from disease due to imbalance of insulin and adipose distributions It helped to adsorb metal ions in animal gut to restore gut disorders [28]
Spirulina platensis Lactobacillus acidophilus, L. Casei, S. thermophilus 5–10 Stimulating growth of lactic acid bacteria Three LAB have been improved in their viability and activity, and suppressed the growth of pathogenic bacteria, improved intestinal adsorption of host [29]
Dunaliella tertiolecta Bacillus sp. ND Development as animal feed, β carotene effect was tested in shrimp Improved immune system and disease resistance [30]
Spirulina platensis, Chlorococcum, D. salina, S. magnus, Chlorella Lactobacillus lactis, Lactobacillus bulgaricus and Bifidobacterium longum Stimulating growth of lactic acid bacteria Xylose and galactose in algal extract stimulate the growth of probiotics [31]
Navicula sp. Lactobacillus sakei ND Developed as animal feed, Oligosaccharide effect was tested Immune system was improved and antioxidant property was enhanced [32]

ND Not determined