Table 1.
Research Subject Demographic Characteristicsa
| Male Sex, n (%) | 40 (57.1) |
|---|---|
| Age (years), median (IQR) | 3.8 (0.2–11.8) |
| Rady Children’s Hospital San Diego, CA, n (%) | 31 (44.3) |
| Children’s Hopsital Orange County, CA, n (%) | 24 (34.3) |
| Nicklaus Children’s Hospital, FL, n (%) | 15 (21.4) |
| Immunocompromised, n (%) | 4 (5.7) |
| Hispanic ethnicity, n (%) | 41 (58.6) |
| Caucasian/White, n (%) | 46 (65.7) |
| African American/Black, n (%) | 2 (2.9) |
| Asian, n (%) | 2 (2.9) |
| Other, n (%) | 12 (28.6) |
| Presenting Symptoms | |
| Fever, n (%) | 51 (72.9) |
| Vomiting, n (%) | 28 (40.0) |
| Seizures, n (%) | 16 (22.9) |
| Lethargy, n (%) | 30 (42.9) |
| Altered Mental Status, n (%) | 26 (37.1) |
| VP shunt, n (%) | 6 (8.6) |
| Received antibitoics prior, n (%) | 28 (40.0) |
| CSF Parameters | |
| Nucleated cells cells/μL, median (IQR) | 109 (35.5–513.5) |
| Erythrocytes cells/μL, median (IQR) | 16 (6.0–368.0) |
| Protein mg/dL, median (IQR) | 97 (41.8–168.0) |
| Glucose mg/dL, median (IQR) | 47.5 (40.0–56.0) |
| Length of stay, median days (IQR) | 6 (3.0–18.5) |
| Admitted to ICU, n (%) | 37 (52.9) |
| Death, n (%) | 3 (4.3) |
| Total Patients | 70 |
Abbreviations: CSF, cerebrospinal fluid; ICU, intensive care unit; IQR, interquartile range; VP, ventriculoperitoneal.
aNOTE: Two unique tubes of residual CSF were received for 1027. Each was processed and analyzed separately by the reference laboratory; both samples produced the same result. The read counts listed in the table represent the mean sequencing reads for these 2 samples.