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Scatter plot of SNPs associated with BMI and the risk of osteoarthritis. The plot presents the effect sizes of the SNP-BMI association (x-axis, SD units) and the SNP-osteoarthritis association (y-axis, log (OR)) with 95% confidence intervals. The regression slopes of the lines correspond to causal estimates using the three Mendelian randomization (MR) methods (the IVW method, weighted median estimator, and MR‐Egger).
