Table 1.
Clinical Characteristics of the 79 Patients Undergoing Carpal Tunnel Release Surgery
| Total cohort (n=79) |
TTR amyloid positive (n=27) |
TTR amyloid negative (n=52) |
P value | |
|---|---|---|---|---|
| Age (years) | 71.6±12.5 | 79.4±6.1 | 67.5±13.0 | <0.001 |
| BMI (kg/m2) | 24.2±4.3 | 23.7±3.0 | 24.6±4.9 | 0.368 |
| Male sex | 32 (41) | 16 (59) | 16 (31) | 0.017 |
| Bilateral CTS | 43 (54) | 18 (67) | 25 (48) | 0.239 |
| Hypertension | 43 (54) | 20 (74) | 23 (44) | 0.017 |
| Dyslipidemia | 29 (37) | 15 (56) | 14 (27) | 0.015 |
| Diabetes | 19 (15) | 4 (15) | 11 (21) | 0.561 |
| Coronary artery disease | 7 (9) | 2 (7) | 5 (10) | 1.000 |
| Atrial fibrillation | 9 (11) | 3 (11) | 6 (11) | 1.000 |
| Dialysis | 15 (19) | 3 (11) | 12 (23) | 0.241 |
| Sodium (mmol/L) | 140.5±2.6 | 140.2±3.0 | 140.7±2.3 | 0.407 |
| Potassium (mmol/L) | 4.2±0.4 | 4.2±0.4 | 4.2±0.4 | 0.490 |
| Creatinine (mg/dL) | 1.9±2.5 | 1.6±1.9 | 2.0±2.7 | 0.406 |
| eGFR (mL/min/1.73 m2) | 56.7±30.2 | 51.8±25.1 | 59.3±32.4 | 0.294 |
| Albumin (g/dL) | 4.1±0.4 | 4.1±0.5 | 4.1±0.4 | 0.811 |
Unless indicated otherwise, data are given as the mean±SD or n (%). BMI, body mass index; CTS, carpal tunnel syndrome; eGFR, estimated glomerular filtration rate, determined using the Modification of Diet in Renal Disease study equation; TTR, transthyretin.