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. 2021 Jun 2;14:3555–3565. doi: 10.2147/OTT.S273794

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© 2021 Wang et al.

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The regulatory functions of PVT1 and miR-551b on FGFR1. (A) The binding sequence between miR-551b and FGFR1 was predicted utilizing miRanda and miRmap. (B) The binding site between miR-551b and FGFR1 was verified using a dual-luciferase reporter gene experiment. (C and D) The effects of miR-551b and PVT1 on FGFR1 mRNA were detected by qRT-PCR. (E and F) The effects of miR-551b and PVT1 on FGFR1 protein expression level were detected employing Western blot. ** and ***Represent P < 0.01 and P < 0.001, respectively.