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. 2021 Jun 7;148(2):368–380.e3. doi: 10.1016/j.jaci.2021.05.032

Fig 2.

Fig 2

Analysis of cytokines, chemokines, and growth factors in BAL fluid of patients with severe COVID-19 (n = 45) and healthy subjects (n = 25). A, BAL fluid concentrations of various cytokines and interferons. B, BAL fluid concentrations of various CC chemokines. C, BAL fluid concentrations of various CXC chemokines. D, Example of positive correlation between CXCL8 and CXCL1. E, Summary of Spearman correlations between cytokines in BAL fluid of subjects with severe COVID-19. F, Diagram showing generation of arachidonic acid following membrane phospholipid hydrolysis by cPLA2 and subsequent processing into various LMs. G, Summary of Spearman correlations between LMs and cytokines in BAL fluid of subjects with severe COVID-19. In this figure, COVID-19 refers to patients with severe COVID-19. Results are presented as scattered plots with median concentrations shown by horizontal bars. ∗∗∗∗P < .0001, as determined using the Mann-Whitney nonparametric test. HS, Healthy subject.