Skip to main content
. Author manuscript; available in PMC: 2021 Jun 7.
Published in final edited form as: Insect Biochem Mol Biol. 2021 Feb 4;133:103548. doi: 10.1016/j.ibmb.2021.103548

Fig. 2.

Fig. 2.

Tissue-specific effects of sestrin on chill coma recovery. (A) Muscle-specific knockdown of sestrin significantly increased time to recovery (n ≥ 25 each group; p < 0.0001; log-rank test). (B) Overexpression of sestrin in muscle did not affect recovery time. (C) sestrin knockdown in nervous system significantly increased time to recovery (n ≥ 39 each group; p = 0.0002; log-rank test). (D) Overexpression of sestrin in the nervous system did not affect time to recovery. (E–F) Manipulating sestrin expression in fat body tissue had no effect on time to recovery.