Table 3.
Adjusted arterial stiffness and load parameters during exercise among HFpEFand hypertensive participants
| HFpEF | HTN control | P-value | |
|---|---|---|---|
| AP (mmHg) | |||
| Rest | 12.80 (7.8) | 10.39 (7.9) | p=0.05 |
| 30w | 1.15 (7.6) | −3.01 (7.6) | p=0.0003 |
| Peak | −6.00 (8.6) | −11.75 (8.6) | p=0.0001 |
| Aix (%) | |||
| Rest | 23.14 (9.2) | 19.55 (9.3) | p=0.01 |
| 30w | 0.45 (9.3) | −4.83 (9.3) | p=0.0002 |
| Peak | −9.06 (11.6) | −16.81 (11.6) | p=0.0001 |
| SVRI (dynes-sec*m2/cm5) | |||
| Rest | 8.10 (0.03) | 8.05 (0.03) | p=0.14 |
| 30w | 7.65 (0.03) | 7.75 (0.03) | p=0.005 |
| Peak | 7.44 (0.03) | 7.28 (0.03) | p<0.0001 |
| EaI (mmHg*m2/ml) | |||
| Rest | 1.37 (0.03) | 1.35 (0.03) | p=0.61 |
| 30w | 1.25 (0.03) | 1.15 (0.03) | p=0.004 |
| Peak | 1.30 (0.03) | 1.16 (0.03) | p=0.0001 |
| TACI ml/mmHg*m2) | |||
| Rest | −0.40 (0.03) | −0.32 (0.03) | p=0.03 |
| 30w | −0.33 (0.03) | −0.19 (0.03) | p=0.0002 |
| Peak | −0.35 (0.03) | −0.20 (0.04) | p<0.0001 |
| PPA (mmHg) | |||
| Rest | 1.37 (0.02) | 1.46 (0.02) | p=0.001 |
| 30w | 1.44 (0.02) | 1.53 (0.02) | p=0.0006 |
| Peak | 1.68 (0.02) | 1.82 (0.03) | p<0.0001 |
Values are expressed as mean (standard error), and values are adjusted for age, sex, body mass index, and presence of diabetes mellitus. AP and Aix also are adjusted for heart rate. Abbreviations: Aix, augmentation index; AP, aortic augmentation pressure; EaI, elastance index; HTN, hypertension; PPA, pulse pressure amplification; SVRI, systemic vascular resistance index; and TACI, total arterial compliance index.