Table 4.
Association of arterial stiffness and load with exercise cardiac performance, including PCWP/CO slope and peak VO2
| Rest r (P-value) | 30W r (P-value) | Peak r (P-value) | |
|---|---|---|---|
| PCWP/CO slope | |||
| AP | 0.17 (0.001) | 0.24 (<0.0001) | 0.24 (<0.0001) |
| Aix | 0.14 (0.008) | 0.19 (0.003) | 0.22 (<0.0001) |
| SVRI | 0.03 (0.60) | 0.18 (0.001) | 0.30 (<0.0001) |
| EaI | 0.01 (0.78) | 0.18 (0.0007) | 0.27 (<0.0001) |
| TACI | −0.10 (0.04) | −0.23 (<0.0001) | −0.27 (<0.0001) |
| PPA | −0.12 (0.02) | −0.19 (0.0003) | −0.23 (<0.0001) |
| Peak VO2 | |||
| AP | −0.05 (0.29) | −0.05 (0.30) | −0.08 (0.14) |
| Aix | −0.09 (0.09) | −0.07 (0.22) | −0.07 (0.15) |
| SVRI | −0.10 (0.06) | −0.08 (0.17) | −0.29 (<0.0001) |
| EaI | −0.11 (0.04) | −0.13 (0.02) | −0.13 (0.01) |
| TACI | 0.10 (0.049) | 0.12 (0.03) | 0.12 (0.03) |
| PPA | 0.04 (0.42) | 0.02 (0.70) | 0.23 (<0.0001) |
Values are expressed as partial correlation coefficient, r, (p-value). Values are adjusted for age, sex, body mass index, and presence of diabetes mellitus. AP and Aix also are adjusted for heart rate. Abbreviations: Aix, augmentation index; AP, aortic augmentation pressure; CO, cardiac output; EaI, elastance index; HTN, hypertension; PCWP, pulmonary capillary wedge pressure; PPA, pulse pressure amplification; SVRI, systemic vascular resistance index; TACI, total arterial compliance index; and VO2, oxygen consumption.