Table 1.
Characteristics of Alzheimer’s disease and control participants.
Healthy controls (n = 42) | Alzheimer’s disease (n = 40) | Difference | |
---|---|---|---|
Age(years) | 81.27(2.48) | 86.72(5.03) | t = 6.270, p < 0.01 |
Sex (males/females) | 19/23 | 23/17 | χ2 = 1.233, p = 0.267 |
Oligomeric Aβ (OD value) | 0.25(0.05) | 0.40(0.10) | t = 6.391, p < 0.01 |
Education (years) | 11.30(3.59) | 11.59(3.64) | t = 0.363, p = 0.717 |
Body mass index | 26.69(3.19) | 25.45(3.72) | t = 1.631, p = 0.107 |
Diabetes | 7.10% | 15% | χ2 = 1.294, p = 0.255 |
Hypertension | 61.90% | 77.50% | χ2 = 2.351, p = 0.125 |
Anti-hypertensive medication | 60.00% | 54.30% | χ2 = 0.249, p = 0.618 |
Anti-hyperlipidemia medication | 64.30% | 50.00% | χ2 = 1.709, p = 0.791 |
Current smoker | 9.50% | 5.00% | χ2 = 0.618, p = 0.432 |
APOE*4 carriers | 19% | 37.50% | χ2 = 3.457, p = 0.063 |
MMSE | 28.21(1.58) | 22.63(3.86) | t = 8.557, p < 0.01 |
Continuous variables are expressed as means and standard deviations. Categorical variables are expressed as %.
APOE*4 apolipoprotein epsilon 4, MMSE Mini-mental state examination.