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. 2021 Jun 7;11:344. doi: 10.1038/s41398-021-01362-2

Table 2.

GLMnet results of lipid models in the classification of AD versus control.

Lipid models Sensitivity Specificity AUC
All_lipids 0.66 0.73 0.78
Cer 0.7 0.79 0.79
ChE 0.78 0.75 0.82
DG 0.72 0.69 0.76
LPC 0.49 0.62 0.58
PC 0.69 0.76 0.78
PE 0.58 0.5 0.57
PI 0.7 0.76 0.79
SM 0.71 0.78 0.83
TG 0.65 0.82 0.83
SM_TG 0.69 0.75 0.81
ChE_SM 0.7 0.81 0.79
ChE_TG 0.71 0.78 0.82
ChE_SM_TG 0.67 0.77 0.79

Cer ceramides, SM sphingomyelins, ChE cholesteryl esters, DG diglycerides, TG triglycerides, PC phosphatidylcholines, LPC lyso-phosphatidylcholines, PE phosphatidylethanolamines, PI phosphatidylinositols, GLMnet elastic net penalization for the generalized linear model.