Table 2.
GLMnet results of lipid models in the classification of AD versus control.
Lipid models | Sensitivity | Specificity | AUC |
---|---|---|---|
All_lipids | 0.66 | 0.73 | 0.78 |
Cer | 0.7 | 0.79 | 0.79 |
ChE | 0.78 | 0.75 | 0.82 |
DG | 0.72 | 0.69 | 0.76 |
LPC | 0.49 | 0.62 | 0.58 |
PC | 0.69 | 0.76 | 0.78 |
PE | 0.58 | 0.5 | 0.57 |
PI | 0.7 | 0.76 | 0.79 |
SM | 0.71 | 0.78 | 0.83 |
TG | 0.65 | 0.82 | 0.83 |
SM_TG | 0.69 | 0.75 | 0.81 |
ChE_SM | 0.7 | 0.81 | 0.79 |
ChE_TG | 0.71 | 0.78 | 0.82 |
ChE_SM_TG | 0.67 | 0.77 | 0.79 |
Cer ceramides, SM sphingomyelins, ChE cholesteryl esters, DG diglycerides, TG triglycerides, PC phosphatidylcholines, LPC lyso-phosphatidylcholines, PE phosphatidylethanolamines, PI phosphatidylinositols, GLMnet elastic net penalization for the generalized linear model.