Table 2.
Brain regionsa | PTSD | Control | PTSD vs. Control | ||||||
---|---|---|---|---|---|---|---|---|---|
N | Mean (mm3) | SD (mm3) | N | Mean (mm3) | SD (mm3) | Diff. (mm3) | Effect sizeb | FDR P | |
Frontal regions | |||||||||
R LOFG | 1259 | 7368.940 | 1137.590 | 2079 | 7562.397 | 1234.104 | −193.456 | −0.111 | 0.000* |
R MOFG | 1232 | 5131.391 | 819.555 | 2071 | 5222.223 | 844.395 | −90.831 | −0.067 | 0.039* |
R IFG-PORB | 1269 | 2696.327 | 497.214 | 2092 | 2764.559 | 515.613 | −68.232 | −0.086 | 0.020* |
R SFG | 1211 | 21834.360 | 3438.285 | 2017 | 22431.852 | 3589.712 | −597.492 | −0.082 | 0.008* |
L LOFG | 1265 | 7565.540 | 1102.285 | 2089 | 7765.323 | 1162.551 | −199.783 | −0.107 | 0.001* |
L MOFG | 1250 | 5160.526 | 889.396 | 2082 | 5288.258 | 907.856 | −127.733 | −0.068 | 0.038* |
L RMFG | 1256 | 15829.645 | 2737.385 | 2081 | 16311.831 | 2959.738 | −482.186 | −0.062 | 0.039* |
Insular regions | |||||||||
R IG | 1118 | 6780.865 | 1006.828 | 1880 | 6847.068 | 974.675 | −66.203 | −0.073 | 0.039* |
L IG | 1197 | 6853.961 | 1050.529 | 2014 | 6962.180 | 1112.211 | −108.219 | −0.066 | 0.036* |
Cingulate regions | |||||||||
L RACC | 1258 | 2684.630 | 589.660 | 2090 | 2758.639 | 596.734 | −74.009 | −0.074 | 0.047* |
L CACC | 1266 | 1848.427 | 495.657 | 2090 | 1939.267 | 525.090 | −90.840 | −0.098 | 0.030* |
L PCC | 1270 | 3242.812 | 590.116 | 2095 | 3341.209 | 626.234 | −98.397 | −0.078 | 0.039* |
Temporal regions | |||||||||
R STG | 1209 | 11434.388 | 1684.942 | 2035 | 11652.213 | 1787.315 | −217.825 | −0.081 | 0.021* |
R MTG | 1249 | 11768.208 | 1932.620 | 2074 | 11941.835 | 2240.106 | −173.627 | −0.075 | 0.020* |
L STG | 1207 | 12107.253 | 1911.582 | 1989 | 12438.862 | 1913.769 | −331.609 | −0.089 | 0.018* |
L STS-banks | 1122 | 2538.936 | 513.020 | 1879 | 2631.318 | 562.580 | −92.382 | −0.084 | 0.039* |
Parietal regions | |||||||||
R precuneus | 1258 | 10119.110 | 1660.468 | 2091 | 10336.908 | 1758.257 | −217.798 | −0.065 | 0.038* |
R SPG | 1153 | 13072.242 | 2171.277 | 1974 | 13293.998 | 2176.036 | −221.756 | −0.068 | 0.039* |
R IPG | 1239 | 15102.197 | 2586.341 | 2066 | 15469.810 | 2754.932 | −367.613 | −0.065 | 0.041* |
L precuneus | 1263 | 9713.105 | 1606.806 | 2093 | 9909.710 | 1672.397 | −196.605 | −0.061 | 0.041* |
Occipital regions | |||||||||
R LING | 1186 | 6786.013 | 1187.746 | 1973 | 6994.104 | 1187.540 | −208.091 | −0.110 | 0.006* |
PTSD vs. control difference significant at FDR corrected P < 0.05 level.
“L” refers to left hemisphere, and “R” means right hemisphere.
The standardized coefficients of linear mixed model were reported for effect sizes.