. Author manuscript; available in PMC: 2021 Oct 30.

Published in final edited form as: Mol Psychiatry. 2020 Dec 7;26(8):4331–4343. doi: 10.1038/s41380-020-00967-1

Table 5.

Cortical regions with significant main effects of PTSD or depression in the analysis including both PTSD diagnosis and depression symptom severity classifications.

	PTSD		Depression
Brain regions	Effect size^a	FDR P	Effect size^a	FDR P
Frontal regions
R LOFG	−0.093	0.020^*	−0.057	0.322
R SFG	−0.066	0.143^†	−0.088	0.107
L LOFG	−0.094	0.020^*	−0.065	0.300
L IFG-POPE	0.024	0.718	−0.143	0.032^#
Insular regions
R IG	−0.025	0.699	−0.128	0.032^#
Cingulate regions
L CACC	−0.106	0.114^†	0.005	0.971
Temporal regions
L STG	−0.049	0.319	−0.128	0.032^#
Parietal regions
R SPG	−0.022	0.718	−0.129	0.032^#
Occipital regions
R LING	−0.076	0.232^†	−0.070	0.322

^*:

PTSD effects were significant at FDR corrected P < 0.05 level in analyses with and without the depression variable.

^{^†:}

PTSD effects were significant at FDR corrected P < 0.05 level in analyses without the depression variable, but were insignificant in analyses with the depression variable.

^{^#:}

Depression effects were significant at FDR corrected P < 0.05 level.

The standardized coefficients of linear mixed model were reported for effect sizes.