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. 2021 May 24;8:651600. doi: 10.3389/fmed.2021.651600

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Copyright © 2021 Xu, Song, Li, Huang, Liu, Bao and Shen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Increased expression of EBLN3P in CRC and its clinical significance. (A) The expression of EBLN3P in 471 CRC specimens and 41 non-tumor specimens from TCGA datasets. (B) The levels of EBLN3P in 95 pairs of primary CRC tissues and the matched non-tumor specimens by RT-PCR. (C,D) Higher levels of EBLN3P were observed in specimens with advanced stages and positive metastasis than those with early stages and negative metastasis. (E) ROC assays for the diagnostic value of EBLN3P expression in CRC specimens. (F) RT-PCR for the levels of EBLN3P in four CRC cell lines (HT29, LoVo, SW480, and HCT116) and human colonic epithelial cell lines NCM46 cells. (G,H) The survival assays of 95 CRC patients according to the mean expression of EBLN3P in 95 CRC specimens. **p < 0.01.