Reagent	Resource	Identifier
Antibodies
Rabbit polyclonal anti-ETS1	Cell Signaling Technology	Cat# 6258BC
Rabbit polyclonal anti-MMP2	Cell Signaling Technology	Cat# 4022, RRID:AB_2266622
Rabbit polyclonal anti-p-AKT	Cell Signaling Technology	Cat# 9271, RRID:AB_329825
Rabbit monoclonal anti-α-TUBULIN	Cell Signaling Technology	Cat# 2125, RRID:AB_2619646
Rabbit polyclonal anti-β-ACTIN	Cell Signaling Technology	Cat# 4967, RRID:AB_330288
Horse anti-rabbit HRP tagged secondary antibody	Cell Signaling Technology	Cat# 7074, RRID: AB_2099233
Goat anti-rabbit IgG Alexa-Fluor 488-labeled secondary antibody	Molecular Probes (Invitrogen)	Cat# A-11008, RRID:AB_143165
Goat anti-rabbit IgG Alexa-Fluor 568-labeled secondary antibody	Thermo Fisher Scientific	Cat# A-21069, RRID:AB_2535730
Chemicals, Peptides, and Recombinant Proteins
Rapamycin	Calbiochem	Cat# 553210; CAS: 67-68-5, 53123-88-9
HIF1α inhibitor	Calbiochem	Cat# 400089; CAS: 329932-55-0
Gelatin	Sigma-Aldrich	Cat# G2500; CAS: 9000-70-8
DAPI	SRL	Cat# 18668; CAS: 28718-90-3
Rhodamine tagged phalloidin	Invitrogen	Cat# R415
SYBR green	Bio-Rad	Cat# 1725120
RNAiso Plus	TAKARA Bio	Cat# 9109
Experimental models: cell lines
Human: PA1	ATCC	Cat# CRL-1572, RRID:CVCL_0479
Human: SKOV3	ATCC	Cat# HTB-77, RRID:CVCL_0532
Critical commercial assays
iSCRIPT cDNA synthesis kit	Bio-Rad	1708891
Nuclear-cytoplasmic isolation kit	Thermo Scientific	Cat# 78833
Cell culture reagents
MEM-α	HIMEDIA	Cat# AL080A
MEM- α (W/O GLN)	HIMEDIA	Cat# AL080
RPMI-1640	HIMEDIA	Cat# AL199A
RPMI-1640 (W/O GLN)	HIMEDIA	Cat# AL060
Oligonucleotides
Primer for ETS1 (Forward: GGAGGACCAGTCGTGGTAAA; Reverse: AACTGCCATAGCTGGATTGG)	[13]	NA
Primer for MMP2 (Forward: TGATCTTGACCAGAATACCATCGA; Reverse: GGCTTGCGAGGGAAGAAGTT)	[13]	NA
Primer for MMP9 (Forward: ACCTCGAACTTTGACAGCGAC; Reverse: GAGGAATGATCTAAGCCCAGC)	[13]	NA
Primer for VIM (Forward: ACACCCTGCAATCTTTCAGACA; Reverse: GATTCCACTTTGCGTTCAAGGT)	[14]	NA
Primer for VEGF (Forward: CTGGAGCGTTCCCTGTGGGC; Reverse: CCTTCCTCCTGCCCGGCTCA)	This paper	NA
Primer for L19 (Forward: GCGGATTCTCATGGAACACA; Reverse: GGTCAGCCAGGAGCTTCTTG)	This paper	NA