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. 2021 May 24;8:675842. doi: 10.3389/fmed.2021.675842

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Copyright © 2021 Zhang, Guo, Yang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Characterization of exosomes from plasma of cSCC and healthy subjects. (A) NTA for detection of the particle size of isolated exosomes. (B) TEM for the appearance of exosomes. Bar = 200 nm. (C) Western blot for examining the expression of exosomal specific markers CD9 and CD63. (D) The junction reads of exosomal circRNAs. (E) The length of exonic circRNAs. (F) The genomic source of exosomal circRNAs.