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The effects of knockdown of ITGB5 or activation of TIMP1 and TMEM176B expression on cell invasion. LNCap cells were transfected by CRISPRi or CRISPRa systems and cell migration assay revealed that knockdown of ITGB5 (A) or activation of TIMP1 (B) and TMEM176B (C) expression inhibited the invasion rate of LNCap cells.
