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. 2021 May 24;11:678824. doi: 10.3389/fonc.2021.678824

Figure 1.

Figure 1

PPIns may be phosphorylated on the 3, 4 and 5 positions to generate seven possible PPIns, each with a different spatial occupancy, that is recognized by different effector proteins. Recruitment of the necessary effector protein is guaranteed by the different accumulation of PPIns in the subcellular compartments. Here are some examples of how different PPIns interact with different effector proteins to convert chemical diversity into diverse functional functions.