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. 2021 May 24;9:639596. doi: 10.3389/fcell.2021.639596

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Copyright © 2021 Liu, Zhang, Huang, Wei, Ning, Li, Liang, Liu and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Construction of the cancer risk and metastasis risk nomograms containing HSP90AA1. LASSO coefficient profiles of the (A) 14 factors in the cancer risk cohort and (D) 21 factors in the metastasis risk cohort. A coefficient profile plot was produced against the logλ sequence. (B,E) Selection results of the LASSO model. The partial likelihood deviance (binomial deviance) curve is plotted versus logλ. Dotted vertical lines are drawn at the optimal values by using the minimum criteria and the 1 SE of the minimum standards (the 1-SE rules). Development of the (C) breast cancer risk nomogram and (F) metastasis risk nomogram. LASSO, least absolute shrinkage and selection operator.