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. 2021 May 24;8:636991. doi: 10.3389/fmolb.2021.636991

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Copyright © 2021 Huang, Jiang, Huang, Zhao, Li and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Validation of the 12-gene signature in the GSE14520 cohort. (A) The distribution and median value of the risk scores in the GSE14520 cohort. (B) PCA plot of the GSE14520 cohort. (C) t-SNE analysis of the GSE14520 cohort. (D) The distributions of OS status, OS, and risk score. (E) Kaplan–Meier curves for the OS of patients in the high-risk group and low-risk group. (F) AUC of time-dependent ROC curves in the GSE14520 cohort.