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. 2021 May 24;9:659392. doi: 10.3389/fcell.2021.659392

FIGURE 5.

FIGURE 5

Restoring the expression of c-Myc reverses BRD7 knockdown-induced effects on cell proliferation and cell cycle progression in colorectal cancer (CRC) cells. (A) The effect of restoring c-Myc expression on BRD7 knockdown-induced cell proliferation inhibition, (B) cell colony formation, and (C) cell cycle G1/S phase arrest. (D) Western blotting confirmed the key molecules regulated by the BRD7/c-Myc axis. The results are presented as the mean ± SD. **P < 0.01, ***P < 0.001.