Fig. 2.

Therapeutic strategies to improve outcomes in COVID-19 patients may include molecules addressing different targets involved in the pathogenesis of the disease. The battery of therapeutic compounds include the following: antivirals (remdesivir, convalescent plasma), molecules with effects against the inflammatory pathways (corticosteroids, tocilizumab, baricitinib), anticoagulants (heparins, DOAC), complement inhibitors (eculizumab, anti-complement C3 antibodies), or compounds reducing endothelial damage (defibrotide, Ang-II pathway antagonists, ACE inhibitors)