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. 2021 May 1;25:11–24. doi: 10.1016/j.omtn.2021.04.022

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© 2021 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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GAS6-AS1 was downregulated in LUAD tissues and correlated with clinical characteristics of LUAD patients

(A) The expression of GAS6-AS1 in different cancer cells is shown from CCLE datasets. (B) GAS6-AS1 was downregulated in 80 LUAD tissues compared with paired adjacent normal tissues. (C) Patients of advanced T stages exerted lower expression of GAS6-AS1. (D) Expression of GAS6-AS1 correlated with tumor size, lymph node metastasis, cancer distant metastasis, and TNM stage of LUAD. (E) GAS6-AS1 was lowly expressed in LUAD cells (A549, H1299, PC9, H1965) compared with HBE cells. (F) GAS6-AS1 was lowly expressed in LUAD tissues in the GEPIA dataset. (G–I) The expression of GAS6-AS1 in LUAD correlated with tumor stage (G), overall survival (H), and disease free (I) survival of patients in the GEPIA dataset.