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. 2021 Apr 30;33(2):256–270. doi: 10.21147/j.issn.1000-9604.2021.02.12

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Aneuploidy subtypes analysis of CTCs and CTECs in different groups. (A) Represent images of chromosomal aneuploidy in CTCs detected by SE-iFISH platform; (B,C) Chromosome 8 aneuploidy of CTCs and CTECs were exhibited by scatter plots, respectively; (D) Chromosome 8 aneuploidy of CTCs and CTECs were exhibited by pie charts, respectively. CTC, circulating tumor cell; CTEC, circulating tumorigenic endothelial cell; SE-iFISH, subtraction enrichment and immunostaining and fluorescence in situ hybridization; DAPI, 4’,6-diamidino-2-phenylindole; CEP8, centromere probe 8; HE4, human epididymis protein 4; CA125, carbohydrate antigen 125; OC, ovarian cancer. **, P<0.01; ***, P<0.001; ns, no significance.