Table 2. Distribution of CA125 and HE4 expression and Chr8 aneuploidy in CTCs and CTECs detected by SE-iFISH in 20 ovarian cancer patients.
Variables | Detection rate of patients [% (n/N)] | Cells proportion [% (n/N)] | |||||
CA125+ | HE4+ | Chr8 aneuploidy | CA125+ | HE4+ | Chr8 aneuploidy | ||
CA125, carbohydrate antigen 125; HE4, human epididymis protein 4; Chr8, chromosome 8; CTC, circulating tumor cell; CTEC, circulating tumorigenic endothelial cell; SE-iFISH, subtraction enrichment and immunostaining and fluorescence in situ hybridization. | |||||||
CTC | 20 (4/20) | 25 (5/20) | 95 (19/20) | 4.8 (10/210) | 4.3 (9/210) | 99.5 (209/210) | |
CTEC | 30 (6/20) | 25 (5/20) | 80 (16/20) | 14.4 (26/180) | 6.1 (11/180) | 100 (180/180) |