Table 3. Optimum cut-off values and their respective sensitivity and specificity.

Index	cut-off	AUC	Sensitivity (%)	Specificity (%)	P	95% CI
CTC, circulating tumor cell; CTEC, circulating tumorigenic endothelial cell; AUC, area under the curve; 95% CI, 95% confidence interval.
CTC	4.5	0.670	75.00	58.30	0.036	0.521−0.820
CTEC	1.5	0.616	80.00	41.57	0.150	0.459−0.773
CTC + CTEC	11.5	0.650	60.00	72.22	0.065	0.496−0.804
Triploid CTC	2.5	0.792	50.00	94.44	<0.001	0.663−0.920
Tetraploid CTC	0.5	0.821	75.00	80.51	<0.001	0.692−0.949
≥Pentaploid CTC	2.5	0.577	70.00	50.00	0.343	0.426−0.728
Triploid + tetraploid CTC	2.5	0.853	70.00	91.67	<0.001	0.738−0.969
Triploid small CTC	1.5	0.760	55.00	86.11	0.001	0.617−0.904
Tetraploid small CTC	0.5	0.781	60.00	94.44	0.001	0.638−0.923
Triploid + tetraploid small CTC	1.5	0.809	70.00	83.30	<0.001	0.674−0.944
Small CTC	3.5	0.745	50.00	94.40	0.003	0.598−0.892
Tetraploid large CTC	0.5	0.740	60.00	86.11	0.003	0.594−0.887
Tetraploid small CTC	0.5	0.675	35.00	100	0.031	0.515−0.835