Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jun 3;17:17448069211021698. doi: 10.1177/17448069211021698

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Figure 4. — No significant effect of NB001 on anxiety-like behavior, locomotor activity, fear memory, and motor function. (a) Representative traces showing the movement of saline- and NB001-injected (10 mg/kg) mice in the EPM for 5 min. (b) There was no significant difference in the number of arm entries (open and closed) between saline-injected (n = 5) and NB001-injected (n = 7) mice. (c) There was no significant difference in the percentage of time spent in the open arms between saline- and NB001-injected mice. (d) Representative traces showing the movement of saline-injected (n = 6) and NB001-injected (n = 6) mice in the open field for 30 min. (e-f) Saline- and NB001-treated mice showed no difference in the open field test. (g) There was no significant difference in latency to fall between saline-injected (n = 5) and NB001-injected (n = 6) mice. In each experiment, mice were given an oral injection of NB001 (10 mg/kg) or saline 30 min before the test. (h) There was no significant difference in fear memory tests (n=6).