Table 1.
Patients’ characteristics including comparison of patients with or without any treatment limitation (PTL)
| Variable | All patients (n = 526) | No limitation (n = 300) | Any limitation (n = 226) | p-value | |||
|---|---|---|---|---|---|---|---|
| n | Median (quartiles) | n | Median (quartiles) | n | Median (quartiles) | ||
| Demographics/vital parameters | |||||||
| Sex (%) | 526 | ♂ 53.4; ♀ 46.6 | 300 | ♂ 55.7; ♀44.3 | 226 | ♂ 50.4; ♀ 49.6 | 0.252 |
| Age (years) | 526 | 73 (57; 82) | 300 | 60 (51; 73) | 226 | 81 (76; 87) | < 0.001 |
| Pulse rate (1/min) | 523 | 84 (76; 95) | 299 | 84 (78; 97) | 224 | 82 (73.3; 94) | 0.065 |
| sBP (mmHg) | 523 | 129 (113; 140) | 299 | 130 (115; 140) | 224 | 126 (110; 140) | 0.162 |
| dBP (mmHg) | 523 | 75 (65; 84) | 299 | 77 (70; 85) | 224 | 70 (60; 80) | < 0.001 |
| Body temperature (°C) | 525 | 37.6 (36.8; 38.4) | 300 | 37.7 (37; 38.5) | 225 | 37.4 (36.7; 38.2) | 0.007 |
| SpO2 (%) | 506 | 94 (91; 96) | 285 | 94 (92; 96.3) | 220 | 93 (90; 96) | 0.002 |
| Laboratory parameters upon admission | |||||||
| Hemoglobin (g/dl) | 524 | 13.3 (11.8; 14.6) | 300 | 13.5 (12.2; 14.8) | 224 | 12.9 (11.3; 14.2) | < 0.001 |
| Hematocrit (%) | 524 | 38.6 (34.5; 42.0) | 300 | 39.4 (35.3; 42.3) | 224 | 37.9 (33.3; 41.7) | 0.007 |
| Thrombocytes (G/l) | 524 | 197.5 (150.0; 252.0) | 300 | 198.5 (152.0; 249.8) | 224 | 190 (148.3; 255.8) | 0.885 |
| Leucocytes (G/l) | 524 | 6.5 (4.7; 8.9) | 300 | 6.1 (4.6; 8.4) | 224 | 6.9 (5.0; 9.8) | 0.001 |
| Lymphocytes (G/l) | 456 | 0.9 (0.7; 1.3) | 262 | 1 (0.7; 1.4) | 194 | 0.9 (0.6; 1.3) | 0.014 |
| Neutrophils (G/l) | 456 | 5.1 (3.4; 7.6) | 262 | 4.7 (3.2; 6.8) | 194 | 5.4 (3.8; 8.5) | 0.001 |
| Creatinine (µmol/l) | 517 | 1.1 (0.9; 1.5) | 294 | 1 (0.8; 1.3) | 223 | 1.4 (1.0; 2.0) | < 0.001 |
| eGFR (ml/min) | 517 | 61.1 (37.9; 82.2) | 294 | 73.6 (55.2; 88.1) | 223 | 42.8 (26.3; 62.2) | < 0.001 |
| ALT (U/l) | 473 | 25.0 (17.4; 39.0) | 271 | 28 (19.6; 43.1) | 202 | 21.9 (15.2; 32.5) | < 0.001 |
| GGT (U/l) | 448 | 41.0 (22.3; 79.0) | 251 | 41 (23.0; 75.0) | 197 | 41 (22.0; 92.5) | 0.591 |
| LDH (U/l) | 419 | 311.0 (231.0; 402.0) | 238 | 309 (229.8; 394.8) | 181 | 315 (235.0; 402.5) | 0.674 |
| CRP (mg/dl) | 519 | 6.0 (2.3; 11.5) | 297 | 5.4 (1.9; 10.2) | 222 | 6.5 (3.1; 12.1) | 0.014 |
| IL-6 (pg/ml) | 91 | 66.5 (27.4; 127.0) | 55 | 73.3 (27.7; 127.0) | 36 | 63.6 (24.8; 128.8) | 0.858 |
Bold p-values represent statistical significance (< 0.05)
sBP systolic blood pressure, dBP diastolic blood pressure, SpO2 pulse oxygen saturation, eGFR estimated glomerular filtration rate, ALT alanine aminotransferase, GGT gamma-glutamyl transferase, LDH lactate dehydrogenase, CRP C-reactive protein, IL-6 Interleukin-6