Figure 3.

Therapeutic evaluation of GD2m-expressing OVs (VV-GD2m or SFV-GD2m)

(A and B) A/J mice bearing a murine neuroblastoma NXS2 tumor were i.t. treated with either PBS or corresponding viruses as indicated on day 7 after tumor implantation. (A–D) The tumor sizes (mean + SEM) (A and C) and Kaplan-Meier survival curves (B and D) were shown. Tumor sizes between each treatment group were compared using two-way ANOVA with Tukey correction, and survival curves were compared using the log-rank test (∗∗∗p < 0.001).