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. 2021 May 5;21:356–366. doi: 10.1016/j.omto.2021.04.016

Figure 7.

Figure 7

Antibody-dependent cellular toxicity induced by serum from VV-GD2m-NAP-treated mice

(A) Relative killing of NXS2 tumor cells in the presence of serum harvested from PBS-, VV-GD2m-, or VV-GD2m-NAP-treated mice (mean ± SEM). One-way ANOVA with Bonferroni correction was used to compare the mean values between groups with each dilution (∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, ∗∗∗∗p < 0.0001). (B) The percentage of IFN-γ+CD107a+ NK cells (gated as CD3−NKp46+) in the ADCC assay, in the presence of serum isolated from PBS-, VV-GD2m-, or VV-GD2m-NAP-treated mice. (mean ± SEM). One-way ANOVA with Bonferroni correction was used to compare the mean values between groups (∗p < 0.05, ∗∗p < 0.01).