Table 1. Primary information for the analyzed ERCC1/2 SNPs in our population.
Genes | SNPs | Major allele (%) | Minor allele (%) | Genotypes | MAF | χ2 | P | ||
---|---|---|---|---|---|---|---|---|---|
Homozygous 1 | Heterozygote | Homozygous 2 | |||||||
ERCC1 | rs11615 | G (79.3) | A (20.7) | GG [55] | GA [28] | AA [4] | 0.4117 | 0.03 | 0.98 |
ERCC1 | rs3212961 | G (50.0) | T (50.0) | GG [22] | GT [43] | TT [22] | 0.1447 | 0.01 | 0.99 |
ERCC1 | rs3212986 | C (70.7) | A (29.3) | CC [43] | CA [37] | AA [7] | 0.2568 | 0.06 | 0.97 |
ERCC2 | rs13181 | T (93.1) | G (6.9) | TT [75] | TG [12] | GG [0] | 0.3689 | 0.48 | 0.79 |
ERCC2 | rs238406 | G (51.1) | T (48.9) | GG [24] | GT [41] | TT [22] | 0.4205 | 0.28 | 0.87 |
ERCC2 | rs1799793 | C (94.8) | T (5.2) | CC [78] | CT [9] | TT [0] | 0.3088 | 0.26 | 0.88 |
SNPs, single-nucleotide polymorphisms; MAF, minor allele frequency.