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. 2021 May;13(5):3126–3136. doi: 10.21037/jtd-21-755

Table 3. Association between the ERCC1/2 gene polymorphisms and prognosis in 87 NSCLC patients who received definitive radiotherapy.

Gene MST (months) 95% CI P Median PFS (months) 95% CI P
rs11615
   AA 6.77 0–14.05 0.000 5.13 0–15.13 0.019
   AG 19.77 11.14–28.40 11.33 5.76–16.91
   GG 30.90 12.83–48.97 18.87 12.56–19.58
A allele 16.17 9.10–23.24 0.024 11.33 8.66–14.01 0.005
G allele 30.90 12.83–48.97 18.87 13.96–23.78
rs3212961
   GG 24.77 4.75–44.79 0.735 11.53 6.41–16.66 0.910
   GT 23.97 15.75–32.19 18.07 12.67–23.47
   TT 24.93 9.37–40.49 11.60 5.28–19.92
G allele 24.93 18.95–30.91 0.441 16.17 11.84–20.50 0.897
T allele 24.77 4.75–44.79 11.53 6.41–16.66
rs3212986
   AA 71.13 0–160.416 0.092 15.53 0–38.01 0.718
   AC 29.10 18.92–39.28 18.70 11.91–25.49
   CC 21.53 12.97–30.09 14.67 8.849–20.49
A allele 30.90 15.68–46.12 0.086 18.01 8.85–20.49 0.423
C allele 21.53 12.97–30.09 14.67 11.89–24.25
rs13181
   TT 24.93 12.67–36.87 0.692 19.07 9.96–28.19 0.921
   TG 24.77 16.19–33.67 16.47 10.17–19.17
rs238406
   TT 16.17 0–36.26 0686 11.33 8.92–13.74 0.143
   TG 28.67 22.72–34.62 21.50 16.86–26.14
   GG 19.80 13.76–25.84 11.30 6.67–15.93
T allele 26.83 21.44–32.22 0.562 16.83 12.16–21.50 0.097
G allele 19.80 13.76–25.84 11.30 6.67–15.93
rs1799793
   CC 25.40 18.74–32.05 0.222 15.53 11.79–19.27 0.411
   CT 19.07 10.48–27.66 16.13 2.89–29.37

NSCLC, non-small cell lung cancer; CI, confidence interval; MST, median overall survival time; PFS, progression-free survival.