Table 3. Univariate analysis and multivariate analysis of factors of progression-free survival.

	Univariate analysis			Multivariate analysis
	HR (95% CI)	P value		HR (95% CI)	P value
Age	0.963 (0.905–1.024)	0.228
Gender	1.003 (0.445–2.260)	0.995
EGFR mutation type	1.029 (0.459–2.311)	0.944
Lines of therapy	0.960 (0.377–2.441)	0.931
Radiotherapy vs. no radiotherapy	2.087 (0.490–8.884)	0.32
Combination therapy versus monotherapy	2.828 (1.083–7.388)	0.034		3.698 (1.329–10.285)	0.012
ECOG performance status
0	Reference			Reference
1	0.118 (0.037–0.381)	<0.001		0.082 (0.024–0.285)	<0.001
2	0.080 (0.022–0.288)	<0.001		0.041 (0.010–0.170)	<0.001