Table 4. Treatment-related adverse events.
| Event | Total patients (n=56) | |
|---|---|---|
| Any grade | Grade 3 or 4 | |
| Any event | 49 (87.5) | 24 (42.9) |
| Fatigue | 17 (30.4) | 4 (7.1) |
| Decreased appetite | 12 (21.4) | 3 (5.6) |
| Nausea | 10 (17.9) | 1 (1.8) |
| Pyrexia | 6 (10.7) | 1 (1.8) |
| Pneumonitis | 10 (17.9) | 1 (1.8) |
| Rash | 5 (8.9) | 1 (1.8) |
| Gingival bleeding | 2 (3.6) | 0 |
| Anemia | 22 (39.3) | 3 (5.6) |
| Leukopenia | 37 (66.1) | 9 (16.1) |
| Thrombocytopenia | 10 (17.9) | 2 (3.6) |
| Elevated ALT or AST | 17 (30.4) | 4 (7.1) |
| Hypothyroidism | 3 (5.6) | 0 |
Number of patients with an event (percent). ALT, alanine aminotransferase; AST, aspartate transaminase.