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. 2021 May 18;17:1181–1312. doi: 10.3762/bjoc.17.90

Scheme 13.

Scheme 13

Continuous-flow condensation for the synthesis of the intermediate 76 to nabumetone (77) and Microinnova mesofluidic scale-up protocol for the synthesis of 78 [118]. Adapted with permission from [118]. Copyright 2011 American Chemical Society.