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The 12 principles of green chemistry.
| Principle | Flow adherence | |
| 1 | prevent waste | ↑ |
| 2 | atom economy | ↑ |
| 3 | less hazardous chemical syntheses | ↑ |
| 4 | design benign chemicals | ↓ |
| 5 | benign solvents and auxiliaries | ↑ |
| 6 | design for energy efficiency | ↑ |
| 7 | use of renewable feed stocks | ↔ |
| 8 | reduce derivatives | ↔ |
| 9 | catalysis (vs stoichiometric) | ↑ |
| 10 | design for degradation | ↔ |
| 11 | real-time analysis for pollution prevention | ↑ |
| 12 | inherently benign chemistry for accident prevention | ↑ |
