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. 2021 May;10(5):2148–2162. doi: 10.21037/tlcr-21-214

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2021 Translational Lung Cancer Research. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Treatment outcomes of ICIs in patients with and without spirometry-defined COPD. (A) Kaplan-Meier curve of OS by spirometry-defined COPD. (B) Kaplan-Meier analysis of the PFS probability by spirometry-defined COPD. COPD patients had a longer median OS (532 vs. 495 days, P=0.93) and median PFS (278 vs. 189 days, P=0.20) compared to non-COPD patients, however the differences did not reach significance. COPD, chronic obstructive pulmonary disease; ICI, immune checkpoint inhibitor; OS, overall survival; PFS, progression-free survival.