Table 1.
Baseline characteristics at ICU admission
| All, n = 1503 | Survivors, n = 837 | Nonsurvivors, n = 666 | p value | |
|---|---|---|---|---|
| Characteristic | ||||
| Age, y | 60 ± 15 | 56 ± 15 | 64 ± 14 | < 0.001 |
| BMI | 27 ± 7 | 28 ± 8 | 27 ± 7 | 0.002 |
| SAPS 3 | 64 ± 17 | 59 ± 14 | 71 ± 16 | < 0.001 |
| SOFA | 14 ± 4 | 13 ± 4 | 15 ± 4 | < 0.001 |
| Duration of symptoms, median (IQR), d | 9 (6–12) | 9 (7–12) | 8 (6–13) | 0.044 |
| Glasgow coma scale | 11 ± 5 | 12 ± 5 | 10 ± 6 | < 0.001 |
| Racea, n (%) | 0.425 | |||
| White | 910 (61) | 460 (60) | 450 (61) | |
| Black | 109 (7) | 51 (7) | 58 (8) | |
| Mix-ethnicity (Pardo) | 413 (28) | 212 (28) | 201 (27) | |
| Asian | 56 (4) | 35 (5) | 21 (3) | |
| Not informed | 15 (1) | 8 (1) | 7 (1) | |
| Sex, n (%) | 0.01 | |||
| Male | 895 (59) | 431 (56) | 464 (63) | |
| Female | 608 (41) | 335 (44) | 273 (37) | |
| Comorbidities, n (%) | ||||
| Asthma | 44 (3) | 25 (3) | 19 (3) | 0.525 |
| Cancer | 148 (10) | 45 (6) | 103 (14) | < 0.001 |
| Cardiovascular disease | 221 (15) | 100 (13) | 121 (16) | 0.077 |
| Chronic kidney disease, dialytic | 45 (3) | 18 (2) | 27 (4) | 0.179 |
| Chronic kidney disease, not dialytic | 107 (7) | 36 (5) | 71 (10) | < 0.001 |
| Chronic pulmonary disease | 89 (6) | 35 (5) | 54 (7) | 0.031 |
| Diabetes | 563 (38) | 258 (34) | 305 (41) | 0.002 |
| Hypertension | 850 (57) | 401 (52) | 449 (61) | 0.001 |
BMI: body mass index, kg/m2; IQR: interquartile range; SAPS 3: Simplified acute Physiology Score 3; SOFA: Sepsis-related Organ Failure Assessment. Data are presented as mean and standard deviation, unless otherwise stated; BMI missing for 137 (9%) patients; SAPS3, missing for 1 patient; SOFA missing for 8 patients
aThe categories represent the Brazilian official race categories; Comparisons were made with t test, Mann–Whitney U tests or Chi-square test as appropriate