Table 1.

Summary of the RPE layer and single-cell level characteristics extracted from the 14 analysed samples.

	Number of cells	Area (µm2)	Circularity (0–1)	Eccentricity (0–1)	Solidity (0–1)	Intensity (0–1)	Centroid shift (pixels)	CMDCV	Number of neighbours	Colony density (cells/mm2)	Cell coverage (%)	Analysis time (s)
Mean	6864	243	0.83	0.67	0.92	0.42	0.29	0.19	5.22	3249	91	52
SD	869	82	0.01	0.02	0.00	0.06	0.06	0.01	0.05	902	7	10
Min	5012	175	0.81	0.64	0.91	0.31	0.19	0.17	5.12	1797	74	42
Max	8452	400	0.84	0.70	0.92	0.51	0.39	0.20	5.31	4237	100	75
Median	6984	193	0.83	0.67	0.92	0.44	0.29	0.19	5.21	3743	90	48
IQR	995	141	0.01	0.02	0.00	0.04	0.08	0.02	0.06	1687	9	12
Shapiro–Wilk’s p value	0.98a	0.00	0.01	0.67a	0.00	0.02	0.69a	0.03	0.94a	0.01	0.21	0.08
Skewness	−0.31a	0.67	−0.45	−0.11a	−1.25	−0.77	0.14a	−0.48	−0.06a	−0.45	−0.80	0.84

CMD_CV: coefficient of variation of RPE cellular membrane mask.

^aValues that fulfil the requirements for normality.