Table 2.

Hazard ratios derived by Cox models for certain events: visual acuity ≥ 70 ETDRS letter, visual acuity dropping below 70 letters in patients that reached VA above 70 ETDRS letters under therapy and vision loss of more than 15 ETDRS letters.

	Hazard ratio		Lower		Higher		p value
Cox model for visual acuity ≥ 70 ETDRS letters
Gender—Male	1.13	(	1.03	–	1.24	)	<0.001
Age @ baseline	0.99	(	0.98	–	0.99	)	<0.001
VA @ baseline	1.09	(	1.09	–	1.1	)	<0.001
Number of injections	1.18	(	1.14	–	1.22	)	<0.001
Cox model for visual acuity ≤ 69 in those that have reached VA ≥ 70
Gender—Male	0.92	(	0.82	–	1.04	)	0.172
Age @ baseline	1.01	(	1.01	–	1.02	)	<0.001
VA @ baseline	0.97	(	0.96	–	0.97	)	<0.001
Number of injections	0.96	(	0.93	–	0.99	)	<0.01
Cox model for visual acuity loss of more than 15 ETDRS letters
Gender—Male	0.88	(	0.74	–	1.04	)	0.130
Age @ baseline	1	(	0.99	–	1.01	)	0.999
VA @ baseline	1.01	(	1	–	1.01	)	<0.05
Number of injections	0.98	(	0.96	–	1	)	<0.05