TABLE 3.

Univariate and bivariate logistic regression to evaluate risk factors for severe^∗ clinical presentation of the severe acute respiratory syndrome coronavirus-2 infection, n = 20

	Univariate analysis		Bivariate analysis
	Odds ratio (95% CI)	P value	Odds ratio (95% CI)	P value
Native liver disease LT†	9.2 (2.4–34)	0.001	6.1 (1.5–24)	0.01
NAFLD	12 (2.7–53)	0.001	5.6 (1.19–26.3)	0.02
Non-NAFLD†
Obese	4.5 (1.4–14)	0.008
Nonobese†
Biliary atresia	0.4 (0.11–1.4)	0.1
Nonbiliary atresia†
Female	0.52 (0.18–1.4)	0.2
Male†
Age	1.01 (0.94–1.06)	0.7
Immunosuppression use	0.1 (0.03–0.37)	<0.001
No immunosuppression use†

CI = confidence interval; IS = immunosuppressive medication; LT = liver transplant; NAFLD = nonalcoholic fatty liver disease.

^∗Severe SARS-CoV2 infection defined as pediatric intensive care unit level of care, respiratory failure requiring mechanical ventilation, use of vasoactive medications, use of renal replacement therapy and/or death.

^†Reference group.