Fig. 2.

Bioinformatic prediction of targeting SMAD4 by LAT-derived miRNAs (A) miR-H2, (B) miR-H4, and (C) miR-H5 target SMAD4 3’UTR at different sites. Predicted binding site types are indicated in red, and other complementary pairing bases are shown in gray. TargetScan Custom defines site types as below: 8mer: an exact match to positions 2-8 of the mature miRNA, followed by an 'A'; 7mer-m8: an exact match to positions 2-8 of the mature miRNA; 7mer-1A: an exact match to positions 2-7 of the mature miRNA, followed by an 'A'