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HXZQ-OL reduced the levels of IL-4 mRNA (A) and TNF-α mRNA (B) in IgE/Ag-mediated RBL-2H3 cells. IgE-sensitized RBL-2H3 cells were incubated with HXZQ-OL (43.97, 439.7 and 4397 μg/mL) for 30 min, followed by DNP-BSA challenge for 4 h. The gene expression of IL-4 and TNF-α were measured by RT-qPCR. The data were expressed as the mean ± SD values of three independent experiments. *p < 0.05 and **p < 0.01.
