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. 2021 Jun 6;10(1):1097–1111. doi: 10.1080/22221751.2021.1925594

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Light-chain VK1-9-encoded antibodies were highly shared among COVID-19 patients. (A) The usage distribution of light-chain germline gene that paired with VH3-53 in 80 known RBD-targeted antibodies[3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14]. (B) Comparison of LCDR3 sequences of the known VK1-9-encoded light chains and their presence in the repertoires of COVID-19 patients and healthy people. (C) Comparison of LCDR3 sequences of the shared VK1-9-J4 clonotype identified from the repertoires of COVID-19 patients and healthy people. (D) The proportion of the VK1-9-J4 clonotype in the total VK1-9 light-chain repertoires of COVID-19 patients and healthy people.