Table 4.
Correlates of Peak Inflammatory Marker Levels in Multivariate Regression Models
| Covariates | D-dimer | CRP | ESR | Ferritin | LDH | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Std β | p-value | Std β | p-value | Std β | p-value | Std β | p-value | Std β | p-value | |
| White race | 1 | – | 1 | – | 1 | – | 1 | – | 1 | – |
| Black race | 0.10 | <0.001* | 0.03 | 0.332 | 0.13 | < 0.001* | 0.09 | 0.001* | 0.11 | <0.001* |
| Age | 0.13 | <0.001* | 0.23 | <0.001* | 0.14 | < 0.001* | 0.09 | 0.004* | 0.06 | 0.027* |
| Male | 1 | –– | 1 | – | 1 | – | 1 | – | 1 | – |
| Female | −0.05 | 0.081 | −0.15 | <0.001* | 0.03 | 0.287 | −0.15 | <0.001* | −0.12 | <0.001* |
| BMI | – | – | 0.06 | 0.042* | 0.09 | 0.004* | – | – | 0.08 | 0.006* |
| Smoking history | – | – | −0.06 | 0.046* | – | – | −0.05 | 0.070 | −0.08 | 0.006* |
| Alcohol use | – | – | – | – | – | – | – | – | – | – |
| Type 2 diabetes | – | – | 0.09 | 0.003* | 0.12 | < 0.001* | – | – | – | – |
| Hypertension | – | – | −0.07 | 0.028* | – | – | −0.06 | 0.047 | – | – |
| Cerebrovascular disease | – | – | – | – | – | – | – | – | 0.06 | 0.052 |
| COPD | −0.06 | 0.042* | – | – | – | – | −0.05 | 0.062 | – | – |
| CKD | – | – | – | – | 0.08 | 0.013* | – | – | – | – |
| ESRD | – | – | 0.11 | <0.001* | – | – | 0.34 | <0.001* | – | – |
| HIV infection | – | – | – | – | – | – | −0.05 | 0.084 | – | – |
| Proteinuria | – | – | – | – | – | – | 0.04 | 0.098 | 0.06 | 0.023 |
Abbreviations: BMI body mass index, CKD chronic kidney disease, CRP C-reactive protein, ESR erythrocyte sedimentation rate, ESRD end-stage renal disease, HIV human immunodeficiency virus, Std β standardized β coefficient, LDH lactate dehydrogenase
“*” denotes statistically significant difference between Black and White patients (p <0.05)