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. 2021 Apr 8;15:1218. doi: 10.3332/ecancer.2021.1218

Table 2. Study design and primary endpoints of clinical trials involving gastrectomy for GC as found on ClinicalTrials.gov as of 1 May 2020.

NA Phase I Phase I/II Phase II Phase II/III Phase III Phase IV Total (%)
Interventional mode
Single group assignment 10 - 2 12 - 1 - 25 (18%)
Parallel assignment 52 2 1 14 3 40 1 113 (82%)
Treatment allocation
Nonrandomised 6 - - - 1 1 - 8 (6%)
Randomised 49 2 1 14 2 39 1 108 (78%)
Not specified 7 - 2 12 - 1 - 22 (16%)
Masking
Open label (none) 42 - 2 24 3 36 - 107 (78%)
Masked 20 2 - 2 - 5 1 30 (22%)
Not specified - - 1 - - - - 1 (1%)
Main primary endpoint
30-day reoperation 1 - - - - - - 1 (1%)
Number of harvested lymph nodes 5 - 1 5 - 3 - 14 (10%)
Operation time 4 - - 1 - 1 - 6 (4%)
Overall survival 4 - - 4 2 15 - 25 (18%)
Percentage body weight ratio - - - - - 1 - 1 (1%)
Postoperative length of stay 3 - - 1 - 1 - 5 (4%)
Postoperative morbidity 6 - 1 2 - 2 - 11 (8%)
Postoperative outcomes 16 - - 5 - 3 1 25 (18%)
Progression-free survival 17 1 - 7 1 12 - 38 (28%)
Quality of life 3 1 - 1 - 3 - 8 (6%)
Rate of conversion - - 1 - - - - 1 (1%)
Time to drain removal 1 - - - - - - 1 (1%)
Tumour recurrence rate 2 - - - - - - 2 (1%)