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. Author manuscript; available in PMC: 2021 Jun 7.
Published in final edited form as: Hum Pathol. 2019 Mar 6;87:95–102. doi: 10.1016/j.humpath.2019.02.006

Table 1.

T-cell densities (cells/mm2) by p53 status in combined matched-race TMA sets

CD3+ density
 CD8+ density
 FOXP3+ density
n (387) Median P a n (388) Median P a n (206) Median P a
Overall
 p53 negative b 367 230.8 .004 * 368 66.3 .1
 p53 positive c 20 341.3 20 90.7
European American
 p53 negative b 192 220.6 .03 * 192 76.9 .4
 p53 positive c 14 301.5 14 88.4
African American
 p53 negative b 175 241.5 .02 * 176 57.0 .05 * 179 15.9 .04 *
 p53 positive c 6 486.3 6 104.8 6 34.0

NOTE. FOXP3 immunostaining was unevaluable on a subset of the European American tumors from the matched-race TMA set because of a faulty batch of slides, which were incompatible with Ventana immunostainer. Thus, these data are not included. CD3 and CD8 immunostaining was unevaluable in 4 and 3 African American cases from the race TMA set because of poor staining, respectively.

a

Kruskal-Wallis test.

b

Absence of p53 nuclear accumulation.

c

Presence of p53 nuclear accumulation.

*

P < .05.