Table 2.

T-cell densities (cells/mm²) by clinicopathological parameters and p53 status in intermediate/high-risk TMA sets

	CD3+ density			CD8+ density			FOXP3+ density
	n (257)	Median	P b	n (262)	Median	P b	n (239)	Median	P b
Race
White	233	215.7	.3	237	69.0	.1	218	30.5	.2
Nonwhite a	24	193.6		25	45.1		21	22.1
Stage
T2 N0	73	205.1	.3	74	65.9	0.2	66	26.1	.1
T3aN0	110	212.2		110	62.8		102	30.9
T3bN0	32	208.7		35	84.0		33	28.3
T4 N0	0	0.0		0	0.0		0	0.0
N0	215	207.8	.1	219	67.2	.9	201	28.3	.1
N1	39	277.6		40	68.1		36	34.5
Gleason score
6	1	308.6	.7	1	247.6	.5	1	59.2	.2
3 + 4	109	209.6		111	67.2		99	29.2
4 + 3	51	231.7		53	71.6		50	29.2
8	29	183.9		30	57.5		28	22.1
9	64	233.4		64	70.0		59	33.6
p53 negative c	241	207.8	.006 *	245	66.3	.5	222	29.2	.04 *
p53 positive d	16	415.9		17	71.6		17	51.3

NOTE. CD3, CD8, and FOXP3 immunostaining was unevaluable in 10, 5, and 28 cases from the intermediate/high-risk TMA set because of poor staining, respectively. Tumor stage and Gleason score information was not available for a few cases.

^aIncluding African American, Hispanic, other, and unknown.

^bFrom Kruskal-Wallis test.

^cAbsence of p53 nuclear accumulation.

^dPresence of p53 nuclear accumulation.

^*P < .05.