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. Author manuscript; available in PMC: 2021 Jun 7.

Published in final edited form as: Hum Pathol. 2019 Mar 6;87:95–102. doi: 10.1016/j.humpath.2019.02.006

Table 3.

T-cell densities (cells/mm²) by clinicopathological parameters and p53 status in primary Gleason pattern 5 TMA sets

	CD3+ density			CD8+ density			FOXP3+ density
	n	Median	P ^a	n	Median	P ^a	n	Median	P ^a
Overall	77	379.4		77	103.5		77	5.3
Race
White	64	369.7	.9	64	107.9	.9	64	5.3	.9
Nonwhite ^b	13	382.1		13	96.4		13	6.2
Stage
T2 N0	10	413.1	.04 ^*	10	100.0	.02 ^*	10	6.6	.6
T3aN0	23	267.7		23	74.3		23	4.4
T3bN0	27	423.7		27	102.6		27	4.4
T4 N0	1	270.4		1	112.3		1	1.8
N0	61	292.6	.01 ^*	61	92.9	.001 ^*	61	4.4	.2
N1	16	773.5		16	256.1		16	6.2
Secondary Gleason pattern
4	72	380.8	.9	72	107.9	.9	72	5.8	.1
5	5	359.9		5	92.9		5	3.5
p53 negative ^c	58	344.0	.01 ^*	58	107.5	.1	58	4.4	.3
p53 positive ^d	12	661.8		12	203.9		12	7.1

NOTE. p53 immunostaining was unevaluable in 7 cases from the Gleason pattern 5 TMA set.

^a

From Kruskal-Wallis test.

^b

Including African American, Hispanic, other, and unknown.

^c

Absence of p53 nuclear accumulation.

^d

Presence of p53 nuclear accumulation.

^*

P < .05.